Support Materials for CD-ROM
This program is intended to provide an introduction to psychiatric genetics, with a focus on the genetics of common complex disease, for genetics professionals. The content includes discussion of complex disease, overview of psychiatry, research in psychiatric genetics, unipolar depression, bipolar disorder, schizophrenia, and issues in psychiatric genetic counseling.
Counseling Aids
- Empiric risk data
- Age-at-onset curves
- Questions to help identify individuals with psychiatric illness
- Teratogen information
- ELSI information
- Psychotropic medications lists
- Glossary of psychiatric terms (Courtesy of the NSGC)
- Support groups
Genetic Disorders with Psychiatric Phenotypes
Some genetic disorders can cause psychiatric phenotypes in a proband, even in the absence of a family history. Genetic disorders that may have psychiatric manifestations (although generally in a small subset of patients) include:
- Velocardiofacial disorder (22q deletion)
- Homocystinuria
- Metachromatic leukodystrophy, late-onset
- Coproporphyria
- Acute intermittent porphyria
- Wolfram syndrome
- Fragile X syndrome
This list is not intended to be comprehensive, and does not include disorders that cause severe phenotypes in childhood (for instance Rett, Prader-Willi, and Smith-Magenis syndromes), as those individuals likely will not be ascertained through psychiatric features.